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Heart valve Control the direction of blood flow through the four
chambers of the heart (two atrium and two ventricles). The
valves act likes one-way door and stop blood from running back wards.
Blood
that has been pumped around the body returns to the heart by
large veins and flow into the right atrium then through the
tricuspid valve into the right ventricle. From here, blood is
pumped through the pulmonary valve to the lung to pick up
oxygen. The blood then re-enters the heart into the left atrium
through the Pulmonary veins and goes to the left ventricle
through the Mitral Valve. From the
left ventricle the blood is pumped through the aortic valve into
the aorta and on to the rest of the body. |
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Heart Valve Diseases |
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Congenital: |
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Some
people are born with abnormal valve. In aortic position it can
have one or two leaflet instead of normally three leaflets.
These valves produce abnormal turbulence and later calcify to
produce obstruction in the blood flow. These children may need
attention to their valvular problem at the early age. Similarly
mitral valve also can have defects from birth, which may need
attention at early age. |
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Acquired valvular disease: |
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This is mostly due to rheumatic fever.
This is sequel of Group–A Streptococcal-tonsillopharyngytis infection of the
throat. This involves mainly major joints and heart. Cardiac
symptoms are mainly inflammatory lesions of heart valves.
Eventually it will lead to cicatrisation and deformity of valve
at a later date. |
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Rheumatic valvular
heart disease may lead to obstruction, or leakage
of the heart valve and many a time both can co-exist. It
is the left sided heart valves
(Mitral or Aortic) which get commonly affected. Usually
it takes 7-10 yrs after rheumatic fever before the
symptoms of heart valve disease appear. Apart from this
heart valve can be damaged due to direct infection of
the valve itself. This is called
infective endocarditis. |
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Effects of heart valve Disease
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When a heart valve is damaged the heart
has to work harder to pump through the obstruction. This
together with leakage of valve causes heart to work harder. The
over worked heart may begin to fail causing symptoms of
breathlessness, pain, tiredness and build up fluid in the body.
When this happens the valve needs to be repaired or replaced.
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Rheumatic aortic Stenosis |
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Valve
Repair |
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Sometimes the obstructed valve can be
opened surgically by splitting open the fused area. Also the
leaking valve can be repaired by excising the redundant or
prolapsed segment and by preventing dilation of the valve by a
prosthetic ring.
Valve repairs have important role while
operating on children and women of childbearing age where
anticoagulation can be avoided. |
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Valve
Replacement |
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If it is not possible to repair the valve
then it is replaced with a prosthetic material. A new valve is
sewn into its place by open-heart surgery.
There are different types of valves
available in market. Biological valves are made from human or
animal tissue. The advantage of this valve is that there is no
need for anticoagulation tablets after 3 months. However these
valves have limited life span and start degenerating beyond ten
years. Therefore these valves are usually implanted over the
age of 65 yrs or those patients who
wants to avoid anticoagulation tablets.
Mechanical valves are made from an alloy
of several metals. This alloy is called
Pyrolytic Carbon. These valves last forever. However because
they are not made from natural tissue it is necessary to take
anticoagulation tablets life long to prevent clot formation over
the valve. For maintaining adequate level of anticoagulation it
is necessary to do regular blood test (called INR test)
This can be done in
any standard laboratory and the desired valve should be
2-2.5. Higher INR is associated
with bleeding problem. It starts with gum or nasal bleeding and
may lead to bleeding inside stomach and brain. Sometimes it may
be fatal. Similarly low INR level
< 2.0
may lead to clot formation over the valve which may then go to
any organs of the body, leading to paralysis or other organ
dysfunction. Therefore it is extremely important to do this test
regularly and consult your doctor.
Similarly avoiding infection to any part of the body, specially
teeth and oral cavity and urinary tract is very important. This
may lead to infection of the heart valve called prosthetic valve
endocarditis, which is very difficult to treat. Therefore it is
essential to take antibiotic prophylaxis before any kind of
dental manipulation or other surgical procedure. |
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Mitral Valve replacement |
Mechanical Prosthetic Heart Valves |
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Bioprosthetic Heart Valves |
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